Accéder directement au contenu Accéder directement à la navigation
Article dans une revue

Towards a [4+2] Route to (+/-)-decarestrictines J and H: Synthesis of a Bicyclic Key-intermediate

Abstract : Towards a [4+2] Route to ()-decarestrictines J and Towards a [4+2] Route to ()-decarestrictines J and Towards a [4+2] Route to ()-decarestrictines J and Towards a [4+2] Route to ()-decarestrictines J and Towards a [4+2] Route to ()-decarestrictines J and Sopa Chewchanwuttiwong [a], Arnaud Martel [b], Duang Buddhasukh [a], Eric Brown [b], Sopa Chewchanwuttiwong [a], Arnaud Martel [b], Duang Buddhasukh [a], Eric Brown [b], Sopa Chewchanwuttiwong [a], Arnaud Martel [b], Duang Buddhasukh [a], Eric Brown [b], Sopa Chewchanwuttiwong [a], Arnaud Martel [b], Duang Buddhasukh [a], Eric Brown [b], Sopa Chewchanwuttiwong [a], Arnaud We describe here the development of an approach to the synthesis of 3-oxo-7-hydroxy-9-decanolides of biological interest. This strategy involves two key steps : the inverse electron demand Hetero-Diels-Alder reaction of an original dienophile (1,5-dimethoxy-cyclohexa-1,4-diene), which will ensure the construction of an advanced structure in a very short number of steps, and the ring opening of a functionalized bicyclic lactol, leading to the requisite decanolide. The diastereocontrolled synthesis of such a lactol will be detailed in this communication.
Type de document :
Article dans une revue
Liste complète des métadonnées

https://hal-univ-lemans.archives-ouvertes.fr/hal-02313828
Contributeur : Arnaud Martel <>
Soumis le : lundi 14 octobre 2019 - 09:11:34
Dernière modification le : mercredi 25 mars 2020 - 09:20:25

Identifiants

  • HAL Id : hal-02313828, version 1

Collections

Citation

Sopa Chewchanwuttiwong, Arnaud Martel, Duang Buddhasukh, Eric Brown, Florian Gallier, et al.. Towards a [4+2] Route to (+/-)-decarestrictines J and H: Synthesis of a Bicyclic Key-intermediate. Chiang Mai J. Sci, 2004, 31, pp.181 - 184. ⟨hal-02313828⟩

Partager

Métriques

Consultations de la notice

11